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Come Inside... => The Medical Centre => Topic started by: TG on January 30, 2009, 12:22:09 PM

Title: Gout
Post by: TG on January 30, 2009, 12:22:09 PM
What a bastard!

Gout again in the foot regions. Hobbling around the house on crutches or whizzing round the kitchen on an office chair.

The irony is I was given a prescription for preventative medication and I got up in the morning I was supposed to go and get them with agonising foot pains.

Cant take the pills till the attack has passed.  angry041:

My doctor blames booze but he is a idiot.  ;D

Interestingly I saw another doctor last year at Mrs TG's place of work and he said quite candidly that no-one really knows the actual cause.

So I am going to get pissed so I cant feel anything below the knees.  happy088
Title: Re: Gout
Post by: Barman on January 30, 2009, 12:23:52 PM
What a bastard!

Gout again in the foot regions. Hobbling around the house on crutches or whizzing round the kitchen on an office chair.

The irony is I was given a prescription for preventative medication and I got up in the morning I was supposed to go and get them with agonising foot pains.

Cant take the pills till the attack has passed.  angry041:

My doctor blames booze but he is a idiot.  ;D

Interestingly I saw another doctor last year at Mrs TG's place of work and he said quite candidly that no-one really knows the actual cause.

So I am going to get pissed so I cant feel anything below the knees.  happy088
It seems that you have everything covered!  ;D
Title: Re: Gout
Post by: Nick on January 30, 2009, 12:25:12 PM
I remarked to someone earlier that we all seem to be suffering at present

Pastis's knee
Our worms
Wenchy's nether regions
TMR ditto
Snoopy always
BM's sunburn
GOS in general

They are out to get us, I tells ya
Title: Re: Gout
Post by: Barman on January 30, 2009, 12:26:16 PM
I remarked to someone earlier that we all seem to be suffering at present

Pastis's knee
Our worms
Wenchy's nether regions
TMR ditto
Snoopy always
BM's sunburn
GOS in general

They are out to get us, I tells ya
eeek: I don't have sunburn...  noooo:
Title: Re: Gout
Post by: Bar Wench on January 30, 2009, 12:34:09 PM
I was going to say I don't have nether regions but that doesn't seem right!  rubschin:
Title: Re: Gout
Post by: Pastis on January 30, 2009, 01:26:02 PM
Well, he's right about my knee but happy to say it seems to be repairing nicely, if slowly. Fortunately one of my sticks has a rubber ferrule.
Title: Re: Gout
Post by: grumpyoldsoldier on January 30, 2009, 08:50:40 PM
I remarked to someone earlier that we all seem to be suffering at present

Pastis's knee
Our worms
Wenchy's nether regions
TMR ditto
Snoopy always
BM's sunburn
GOS in general

They are out to get us, I tells ya
General Gos.. I like that it has  a certain ring.

Gout.. a link
http://arthritis.about.com/od/gout/Gout_Information_Causes_Diagnosis_Symptoms_Treatment.htm
Title: Re: Gout
Post by: Nick on January 30, 2009, 09:01:49 PM
Is a rubber ferrule a good thing, do we think?
Title: Re: Gout
Post by: grumpyoldsoldier on January 30, 2009, 09:05:55 PM
Depends on what it is attached to I would think eeek:
Title: Re: Gout
Post by: Nick on January 30, 2009, 09:23:11 PM
He seems to be pleased with it
Title: Re: Gout
Post by: Pastis on January 30, 2009, 10:08:05 PM
Indeed, I am pleased with the rubber ferrule; my other metal ones tend to skid on the pavement when pressure is applied  redface:

However, the prognoscis (sp?) is not good  angry041:





In fact, fvckety fvckety fvckety fvckety fvckety fvckety fvckety fvck!
Title: Re: Gout
Post by: Snoopy on January 31, 2009, 09:06:06 AM
Quote
At the end of December the National Institute for Health and Clinical Excellence (NICE) approved the use of febuxostat as an option in the treatment of chronic hyperuricaemia in gout. NICE stipulates that febuxostat should only be prescribed for people who are "intolerant" of allopurinal or for whom allopurinol is contra-indicated (especially those with kidney failure). Allopurinol has for decades  been the mainstay treatment for gout and works by reducing by reducing the level of serum uric acid concentration in the blood.
At first glance this recommendation seems fairly straightforward but a closer reading of the guidance suggests a more complex picture. The guidance notes that the manufacturer's submission showed that febuxostat is more effective in lowering serum uric acid concentration than fixed-dose allopurinol (300mg per day). When comparing febuxostat at 80mg per day with allopurinol at 300 or mg per day,  no significant differences were found in the numbers of patients requiring treatment for gout flares. However, there was a higher number of patients taking 120mg febuxostat who required treatment.
The guidance expresses concern that the comparisons submitted to it may not be adequate as febuxostat is measured against fixed-dose allopurinol whereas both the European and British best practice guidance recommends that allopurinol be started at a low dose (50 or 100mg) per day and then raised until the therapeutic target is met. The recommended maximum dose is 900 mg per day. The guidance also acknowledges that the vast majority of doctors ignore this guidance and simply prescribe 300mg of allopurinol per day.
So, while the evidence submitted may not reflect best practice, comparing febuxostat with 300mg of allopurinol does give a more realistic picture in terms of how gout is actually treated. NICE also states that it took evidence from specialist doctors who pointed out that many people have high serum acid concentration but that comparatively few of these develop gout and that there was some uncertainty about the precise relationship between lowering serum uric acid concentration and improvement in gout symptoms. NICE nevertheless feels that it is reasonable to assume that gout symptoms begin to occur once serum uric acid levels go above 6mg per 100ml.
The European League Against Rheumatism's (EULAR) recommednations for the treatment of gout recommend that allopurinol should be started on a low dose (100mg per day) and gradually increased by 100 mg every two to four weeks if required, it lists the benefits of this "go low, go slow" approach as;

reduced likelihood of provocation of acute attacks;
reduced incidence of toxicity;
tailoring of the dose to suit individual requirements;
an emphasis on the importance of a sufficintly low target level of serum uric acid.
These all appear eminently sensible- we have to ask why they haven't been put into clinical practice.
I've gone into detail about this so that may readers may appreciate what a convoluted and complex process the approval of even fairly straightforward drugs is.  Patients often assume that medical science is fairly objective and precise whereas most of it is based on half-understood principles and partial data.

Title: Re: Gout
Post by: Miss Demeanour on January 31, 2009, 09:37:36 AM
I remarked to someone earlier that we all seem to be suffering at present

Pastis's knee
Our worms
Wenchy's nether regions
TMR ditto
Snoopy always
BM's sunburn
GOS in general

They are out to get us, I tells ya

That can be painful  lol:

Glad to see theres nowt wrong with me - apart from spelling, grammar, general stupidity,  being a wumman etc etc etc  lol:
Title: Re: Gout
Post by: Snoopy on January 31, 2009, 09:39:38 AM
I remarked to someone earlier that we all seem to be suffering at present

Pastis's knee
Our worms
Wenchy's nether regions
TMR ditto
Snoopy always
BM's sunburn
GOS in general

They are out to get us, I tells ya

That can be painful  lol:

Glad to see theres nowt wrong with me - apart from spelling, grammar, general stupidity,  being a wumman etc etc etc  lol:

Wait till BM's homebrew and figs have done their job.  whistle:
Title: Re: Gout
Post by: Miss Demeanour on January 31, 2009, 09:46:25 AM
Don't do figs  sick2:...or homebrew...

Do you reckon I might have to bring my own food - could  I get a box of Cadbury's giant buttons past customs  ??? whacky115
Title: Re: Gout
Post by: Snoopy on January 31, 2009, 09:49:18 AM
Don't do figs  sick2:...or homebrew...

Do you reckon I might have to bring my own food - do you reckon i could get a box of Cadbury's giant buttons past customs  ??? whacky115

Depends where you hide them ~ Chocolate wouldn't normally show up on an xray.
I understand that LL is an excellent cook ~ just watch the homebrew, the figs and the old goat.
Title: Re: Gout
Post by: Just One More on January 31, 2009, 09:56:32 AM
Take your own cruet, you'll save a fortune
Title: Re: Gout
Post by: Snoopy on January 31, 2009, 09:58:21 AM
Take your own cruet, you'll save a fortune

Indeed ~ It's chips with everything since he got his new chip fryer. You'll need the salt and ketchup I expect.
Title: Re: Gout
Post by: Nick on January 31, 2009, 10:11:36 AM
Can we talk about gout?
Title: Re: Gout
Post by: Miss Demeanour on January 31, 2009, 10:11:49 AM
I was only planning on a taking a little suitcase  eeek:
Title: Re: Gout
Post by: Miss Demeanour on January 31, 2009, 10:14:00 AM
Can we talk about gout?
gout
Title: Re: Gout
Post by: Nick on January 31, 2009, 10:14:11 AM
Miss D's packing list:

Bikini
Ketchup
Salt
DVDs


er.....that's it

oh, cardigan
Title: Re: Gout
Post by: Barman on January 31, 2009, 10:14:41 AM
Can we talk about gout?
gout
Enough of gout... back to your trip...

I could show you my shins...  cloud9:
Title: Re: Gout
Post by: Miss Demeanour on January 31, 2009, 10:15:41 AM
What -  for me to kick them  lol:
Title: Re: Gout
Post by: Barman on January 31, 2009, 10:26:47 AM
What -  for me to kick them  lol:
(https://www.virtual-pub.com/SMF/proxy.php?request=http%3A%2F%2Fwww.freesmileys.org%2Fsmileys%2Fsmiley-sick032.gif&hash=3d1d2d51f3033f967ef07033998b63f0734032ec) (http://www.freesmileys.org)
Title: Re: Gout
Post by: Bar Wench on January 31, 2009, 02:04:42 PM
After his last incident there are bound to be some repairs for you to do!  whistle:
Title: Re: Gout
Post by: Barman on January 31, 2009, 02:05:27 PM
After his last incident there are bound to be some repairs for you to do!  whistle:
Ah... some tender loving care eh...?  cloud9:
Title: Re: Gout
Post by: Nick on January 31, 2009, 02:05:55 PM
Miss D will have to take her nurse's uniform
Title: Re: Gout
Post by: Bar Wench on January 31, 2009, 02:34:50 PM
After his last incident there are bound to be some repairs for you to do!  whistle:
Ah... some tender loving care eh...?  cloud9:

I was thinking more to floors and that sort of thing really!  whistle:
Title: Re: Gout
Post by: Barman on January 31, 2009, 02:36:05 PM
After his last incident there are bound to be some repairs for you to do!  whistle:
Ah... some tender loving care eh...?  cloud9:

I was thinking more to floors and that sort of thing really!  whistle:
Yes, well I don't think we need dwell on this subject any longer...  noooo:

Gout then...  whistle:
Title: Re: Gout
Post by: Miss Demeanour on January 31, 2009, 02:50:47 PM
After his last incident there are bound to be some repairs for you to do!  whistle:
Ah... some tender loving care eh...?  cloud9:

I was thinking more to floors and that sort of thing really!  whistle:

I have been told by BM to get a work permit and that the EU Working Time Regulations don't actually apply over there  eeek:




Title: Re: Gout
Post by: Barman on January 31, 2009, 03:03:44 PM
After his last incident there are bound to be some repairs for you to do!  whistle:
Ah... some tender loving care eh...?  cloud9:

I was thinking more to floors and that sort of thing really!  whistle:

I have been told by BM to get a work permit and that the EU Working Time Regulations don't actually apply over there  eeek:





whistle:
Title: Re: Gout
Post by: Nick on January 31, 2009, 03:06:22 PM
Pack a pinny and some marigolds
Title: Re: Gout
Post by: TG on February 05, 2009, 11:31:02 AM
After his last incident there are bound to be some repairs for you to do!  whistle:
Ah... some tender loving care eh...?  cloud9:

I was thinking more to floors and that sort of thing really!  whistle:
Yes, well I don't think we need dwell on this subject any longer...  noooo:

Gout then...  whistle:

I'm cured! It's a miracle!  cloud9:
Title: Re: Gout
Post by: Barman on February 05, 2009, 11:32:57 AM
After his last incident there are bound to be some repairs for you to do!  whistle:
Ah... some tender loving care eh...?  cloud9:

I was thinking more to floors and that sort of thing really!  whistle:
Yes, well I don't think we need dwell on this subject any longer...  noooo:

Gout then...  whistle:

I'm cured! It's a miracle!  cloud9:
Did the cure coincide with Mrs. TG being snowed-in at work like...?  rubschin:
Title: Re: Gout
Post by: Nick on February 05, 2009, 11:33:25 AM
No, it's just that your feet are frozen and you can't feel anything at all  noooo:
Title: Re: Gout
Post by: barmisspah? on February 05, 2009, 02:40:47 PM
I remarked to someone earlier that we all seem to be suffering at present

Pastis's knee
Our worms
Wenchy's nether regions
TMR ditto
Snoopy always
BM's sunburn
GOS in general

They are out to get us, I tells ya

Not forgetting my knees & elbow - fell over in the snow on Monday redface: felt a right idiot, luckily no one was around to see.
Title: Re: Gout
Post by: Barman on February 05, 2009, 03:05:08 PM
I remarked to someone earlier that we all seem to be suffering at present

Pastis's knee
Our worms
Wenchy's nether regions
TMR ditto
Snoopy always
BM's sunburn
GOS in general

They are out to get us, I tells ya

Not forgetting my knees & elbow - fell over in the snow on Monday redface: felt a right idiot, luckily no one was around to see.
You need moon boots...
Title: Re: Gout
Post by: Nick on February 05, 2009, 05:11:48 PM
And cheese graters
Title: Re: Gout
Post by: Grumpmeister on February 05, 2009, 06:07:06 PM
Don't do figs  sick2:...or homebrew...

Do you reckon I might have to bring my own food - could  I get a box of Cadbury's giant buttons past customs  ??? whacky115

Just keep an eye on the bottles of 'real' booze he hands you. If the contents seem to be dissolving the bottle then its BM's special brew.  whistle:
Title: Re: Gout
Post by: TG on March 19, 2009, 11:55:51 AM
Can we move this thread to the medical centre please? So we can all talk about my health problems as well like?

I'm still cured by the way. Not that you lot givva fork.  confused:

Mrs TG being of a medical background is usually able to diagnose her own illnesses for which she has an uncanny ability to invent highly descriptive and never before heard medical terms.

For example, indigestion type pains : 'squashheart'.  noooo:

Or general aches & panes : 'Sore boneache'.  eeek:

She also has the ability to develop medical conditions when someone gives her a general overview of the symptoms.

I may write to 'The Lancet' and see if she can win a prize.




Title: Re: Gout
Post by: Darwins Selection on March 19, 2009, 12:36:16 PM
Can we move this thread to the medical centre please? So we can all talk about my health problems as well like?

I'm still cured by the way. Not that you lot givva fork.  confused:

Mrs TG being of a medical background is usually able to diagnose her own illnesses for which she has an uncanny ability to invent highly descriptive and never before heard medical terms.

For example, indigestion type pains : 'squashheart'.  noooo:

Or general aches & panes : 'Sore boneache'.  eeek:

She also has the ability to develop medical conditions when someone gives her a general overview of the symptoms.

I may write to 'The Lancet' and see if she can win a prize.





(https://www.virtual-pub.com/SMF/proxy.php?request=http%3A%2F%2Fwww.lisa-morgan.com%2Fimages%2Ffaith-healer-web2.jpg&hash=f302c3b3b954a6ea91c1555415eac661123b096b)
Title: Re: Gout
Post by: grumpyoldsoldier on March 23, 2009, 03:46:51 PM
TG, an update for you
A new drug febuxostat (Adenuric) has been approved for people who ar intolerant to the standard treatment, allopurinol
Decision made by NICE
Source Arthritis News April/May edition 2009

www.arthritiscare.org.uk
Title: Re: Gout
Post by: Nick on March 23, 2009, 04:08:00 PM
Quote
febuxostat

Who dreams up these names?  confused:
Title: Re: Gout
Post by: Barman on March 23, 2009, 04:10:12 PM
Quote
febuxostat

Who dreams up these names?  confused:
Prolly the same guy that comes up will Cillit Bang and Ajax...
Title: Re: Gout
Post by: Nick on March 23, 2009, 04:10:43 PM
It looks like a bad hand in Scrabble  noooo:
Title: Re: Gout
Post by: Pastis on March 23, 2009, 04:34:43 PM
I remember as a kid coming home from school and spelling lessons. There was a bottle of washing up liquid in the kitchen...

(https://www.virtual-pub.com/SMF/proxy.php?request=http%3A%2F%2Fwww.postimage.org%2FPq2v8OTi.jpg&hash=c8c23c1f26d7d75eda2fffbe6349dff24c261642) (http://www.postimage.org/image.php?v=Pq2v8OTi)

How come they don't have to spell it properly, thought I  sad32:
Title: Re: Gout
Post by: Miss Demeanour on March 23, 2009, 04:36:46 PM
You were a pedant even then   noooo:

 lol:
Title: Re: Gout
Post by: Barman on March 23, 2009, 04:37:28 PM
I'd never noticed that....  redface:
Title: Re: Gout
Post by: Pastis on March 23, 2009, 04:44:19 PM
You were a pedant even then   noooo:

 lol:

More like early signs of confusion  ;)
Title: Re: Gout
Post by: Miss Demeanour on March 23, 2009, 04:48:00 PM
Signs of an enquiring mind more like  lol:

No wonder I didn't clock it  lol:
Title: Re: Gout
Post by: Nick on March 24, 2009, 08:34:49 AM
At least OMO is a palindrome
Title: Re: Gout
Post by: Darwins Selection on March 24, 2009, 11:15:26 AM
At least OMO is a palindrome
LHR is an aerodrome.
Title: Re: Gout
Post by: Nick on March 24, 2009, 11:22:07 AM
What's this thread about?
Title: Re: Gout
Post by: Barman on March 24, 2009, 12:14:25 PM
 rubschin:


Gout...?  Shrugs:
Title: Re: Gout
Post by: Nick on March 24, 2009, 12:19:12 PM
Quite so, I dimly recall
Title: Re: Gout
Post by: Barman on March 24, 2009, 12:39:36 PM
Well, I don't have gout...  noooo:
Title: Re: Gout
Post by: Miss Demeanour on March 24, 2009, 12:41:16 PM
Well, I don't have grout...  noooo:

better get back out to the shops then  noooo:
Title: Re: Gout
Post by: Nick on March 24, 2009, 01:43:39 PM
 point: point: point: point: point:

 drumroll:
Title: Re: Gout
Post by: Barman on March 24, 2009, 02:17:28 PM
 evil:
Title: Re: Gout
Post by: Bar Wench on March 24, 2009, 03:00:08 PM
At least OMO is a palindrome

(https://www.virtual-pub.com/SMF/proxy.php?request=http%3A%2F%2Ffarm4.static.flickr.com%2F3648%2F3370528309_cdcc5460cf.jpg%3Fv%3D0&hash=22f97c30612be4424fbd16dfab5f3f0372f09098)

Thanks to the pub I knew what it was!
Title: Re: Gout
Post by: Nick on March 24, 2009, 03:03:04 PM
Nuts  noooo:
Title: Re: Gout
Post by: Barman on March 24, 2009, 03:04:31 PM
At least OMO is a palindrome

(https://www.virtual-pub.com/SMF/proxy.php?request=http%3A%2F%2Ffarm4.static.flickr.com%2F3648%2F3370528309_cdcc5460cf.jpg%3Fv%3D0&hash=22f97c30612be4424fbd16dfab5f3f0372f09098)

Thanks to the pub I knew what it was!
What, a palindrome...?
Title: Re: Gout
Post by: Nick on March 24, 2009, 03:06:32 PM
It's like a small cinema that shows only Michael Palin programmes  noooo:
Title: Re: Gout
Post by: Bar Wench on March 24, 2009, 03:07:26 PM
 Banghead
Title: Re: Gout
Post by: Barman on March 24, 2009, 03:10:50 PM
It's like a small cinema that shows only Michael Palin programmes  noooo:
drumroll: